| Stray Purrely StreetAmazing Defenders · 019 | Amazing Defenders | 019 | Rare | €0.26 |
| Stream, Dragon Ruler of DropletsLord of the Tachyon Galaxy · 096 | Lord of the Tachyon Galaxy | 096 | Common | €0.02 |
| Strength in Unity2020 Tin of Lost Memories · 247 | 2020 Tin of Lost Memories | 247 | Ultra Rare | €0.58 |
| Strength of ProphecyReturn of the Duelist · 018 | Return of the Duelist | 018 | Common | €0.06 |
| Strike NinjaInvasion of Chaos · 007 | Invasion of Chaos | 007 | Ultra Rare | €0.11 |
| Strike of the MonarchsThe New Challengers · 067 | The New Challengers | 067 | Common | €0.14 |
| Striker DragonChaos Impact · 098 | Chaos Impact | 098 | Ultra Rare | €0.07 |
| Strike SlashTactical Evolution · 075 | Tactical Evolution | 075 | Common | €0.10 |
| Striping PartnerExtreme Force · 003 | Extreme Force | 003 | Common | €0.05 |
| Stronghold GuardianDuelist Revolution · 006 | Duelist Revolution | 006 | Common | €0.10 |
| Stronghold the Hidden FortressLegacy of Destruction · 071 | Legacy of Destruction | 071 | Common | €0.03 |
| Stronghold the Moving FortressStructure Deck: Machine Re-Volt · 031 | Structure Deck: Machine Re-Volt | 031 | Common | €0.06 |
| Strong Wind DragonRaging Battle · 003 | Raging Battle | 003 | Ultra Rare | $2.33 |
| Stuffed AnimalTournament Pack: 2nd Season · 019 | Tournament Pack: 2nd Season | 019 | Common | $1.83 |
| StumblingInvasion of Chaos · 035 | Invasion of Chaos | 035 | Short Print | €0.04 |
| Stygian DirgeStardust Overdrive · 078 | Stardust Overdrive | 078 | Short Print | €0.26 |
| Stygian SecurityYu-Gi-Oh! 5D's World Championship 2010: Reverse of Arcadia promotional cards · 002 | Yu-Gi-Oh! 5D's World Championship 2010: Reverse of Arcadia promotional cards | 002 | Super Rare | €0.31 |
| Stygian SergeantsYu-Gi-Oh! 5D's World Championship 2010: Reverse of Arcadia promotional cards · 003 | Yu-Gi-Oh! 5D's World Championship 2010: Reverse of Arcadia promotional cards | 003 | Super Rare | $0.14 |
| Stygian Street PatrolDuelist Revolution · 099 | Duelist Revolution | 099 | Secret Rare | €0.10 |
| Suanni, Fire of the Yang ZingDuelist Alliance · 028 | Duelist Alliance | 028 | Super Rare | €1.03 |
| Sublimation KnightToon Chaos · 013 | Toon Chaos | 013 | Super Rare | €0.12 |
| Submareed Tour RideBattle of Chaos · 027 | Battle of Chaos | 027 | Common | €0.03 |
| Submarine FrogCrimson Crisis · 087 | Crimson Crisis | 087 | Common | €0.20 |
| SubmarineroidPower of the Duelist · 008 | Power of the Duelist | 008 | Rare | €0.09 |
| Submersible Carrier Aero SharkGeneration Force · 040 | Generation Force | 040 | Super Rare | €0.27 |
| Subspace BattleBlazing Dominion · 100 | Blazing Dominion | 100 | Common | €0.12 |
| SubstitoadLight of Destruction · 028 | Light of Destruction | 028 | Rare | $0.19 |
| Subsurface Stage DiversSoul Fusion · 080 | Soul Fusion | 080 | Short Print | €0.05 |
| Subterror Behemoth BurrowingInvasion: Vengeance · 085 | Invasion: Vengeance | 085 | Rare | €0.34 |
| Subterror Behemoth DragossuaryRaging Tempest · 083 | Raging Tempest | 083 | Super Rare | $0.11 |
| Subterror Behemoth FiendessCircuit Break · 098 | Circuit Break | 098 | Super Rare | $0.57 |
| Subterror Behemoth PhospheroglacierMaximum Crisis · 083 | Maximum Crisis | 083 | Common | €0.07 |
| Subterror Behemoth SpeleogeistMaximum Crisis · 084 | Maximum Crisis | 084 | Common | €0.07 |
| Subterror Behemoth StalagmoThe Dark Illusion · 084 | The Dark Illusion | 084 | Ultra Rare | $1.45 |
| Subterror Behemoth StygokrakenInvasion: Vengeance · 083 | Invasion: Vengeance | 083 | Super Rare | €0.14 |
| Subterror Behemoth UltramafusInvasion: Vengeance · 084 | Invasion: Vengeance | 084 | Ultra Rare | $1.58 |
| Subterror Behemoth UmastryxThe Dark Illusion · 083 | The Dark Illusion | 083 | Ultra Rare | €5.44 |
| Subterror Behemoth VoltelluricRaging Tempest · 084 | Raging Tempest | 084 | Rare | €0.24 |
| Subterror Cave ClashRaging Tempest · 085 | Raging Tempest | 085 | Super Rare | €0.12 |
| Subterror FiendessMaximum Crisis · 082 | Maximum Crisis | 082 | Super Rare | €0.19 |
| Subterror Final BattleMaximum Crisis · 085 | Maximum Crisis | 085 | Rare | $0.12 |
| Subterror GuruSavage Strike · 094 | Savage Strike | 094 | Common | €0.03 |
| Subterror Nemesis ArcherInvasion: Vengeance · 082 | Invasion: Vengeance | 082 | Secret Rare | €0.45 |
| Subterror Nemesis DefenderRaging Tempest · 082 | Raging Tempest | 082 | Rare | €0.19 |
| Subterror Nemesis WarriorThe Dark Illusion · 082 | The Dark Illusion | 082 | Rare | €0.16 |
| Subterror SuccessionSavage Strike · 077 | Savage Strike | 077 | Common | €0.04 |
| Successor Soul2020 Tin of Lost Memories · 246 | 2020 Tin of Lost Memories | 246 | Ultra Rare | €0.68 |
| Success Probability 0%Shadow of Infinity · 057 | Shadow of Infinity | 057 | Common | €0.07 |
| Succubus KnightLegend of Blue Eyes White Dragon · 117 | Legend of Blue Eyes White Dragon | 117 | Common | €0.04 |
| Succumbing-Song MorganiteRage of the Abyss · 065 | Rage of the Abyss | 065 | Super Rare | $1.27 |